منابع مشابه
In vitro teratology.
The purpose of this conference was to reevaluate the need for and use of in vitro teratology assays; to examine the validation process for in vitro tests; and to discuss progress in the validation of in vitro teratology screens. Participants enthusiastically supported further development of short-term in vivo and in vitro systems both as prescreens for developmental toxicity and as experimental...
متن کاملThe future of teratology research is in vitro
Birth defects induced by maternal exposure to exogenous agents during pregnancy are preventable, if the agents themselves can be identified and avoided. Billions of dollars and manhours have been dedicated to animal-based discovery and characterisation methods over decades. We show here, via a comprehensive systematic review and analysis of this data, that these methods constitute questionable ...
متن کاملBasic Concepts in Teratology
Given this inherent complexity, the text is remarkably well integrated and presents a balanced picture of current knowledge and questions. As in any book written by many authors, the style and quality of chapters vary, but the overall quality of writing is very good. The chapters by Milton Hildebrand ("Walking and Running"), James L. Edwards ("Terrestrial Locomotion Without Appendages"), and Jo...
متن کاملAdvances in Teratology
Due to the scope of the discipline, an annual survey of teratology must encompass a broad spectrum of findings from the bio-medical sciences. The first volume in this series does range topically in including reviews on aspects of cytogenetic, pharmacological, radiobiological, and immunological problems. If a field such as teratology is to be reviewed, one cannot expect a high degree of correspo...
متن کاملThe teratology of autism.
Autism spectrum disorders affect behaviors that emerge at ages when typically developing children become increasingly social and communicative, but many lines of evidence suggest that the underlying alterations in the brain occur long before the period when symptoms become obvious. Studies of the behavior of children in the first year of life demonstrate that symptoms are often detectable in th...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1991
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.94-1567960